"Tranquilize" is a song by Las Vegas-based rock band, The Killers featuring Lou Reed. The song will be featured on the upcoming compilation album Sawdust.

The song was made available for download on iTunes from October 12th, there will also be limited edition etched 7" vinyl of "Tranquilize" available from November 5th, it will feature a lyric from the song hand picked by Brandon Flowers etched onto one side.